Ankylosing Spondylitis Biomarkers and Genes Summary Table
Ankylosing Spondylitis — Biomarkers & Genes
Biomarker / GeneBad ScoreFree PlanPlan With Purchases
hsCRPBIOMARKER>3 mg/L (active)Sleep 7–9h; avoid processed foodsAerobic exercise 30 min, 5×/weekOmega-3 EPA/DHA 2–4g/day; curcumin+piperine; infrared sauna 3×/week
Fecal CalprotectinBIOMARKER>200 μg/gLow-starch diet 30 days; no alcoholDaily live fermented foodsL. rhamnosus GG + B. longum 10–50B CFUL-Glutamine 5–10g; S. boulardii 500mg
25-OH Vitamin DBIOMARKER<40 ng/mLMidday sun 15–30 min, 3–4×/weekExpose arms, legs, torso (10am–2pm)Vitamin D3 2000–5000 IU + K2 MK-7Magnesium glycinate 300–400mg; UVB lamp
IL-17ABIOMARKER>15–20 pg/mL16:8 fasting; 30-min walks daily2× HIIT/week (30s on, 90s off)Resveratrol 500mg; berberine 500mg 2–3×Red light 630–850nm; vitamin A (retinol)
ESRBIOMARKER>20 mm/hr (men)>30 mm/hr (women)Hydration 30–35 ml/kg/dayApply hsCRP lifestyle protocolNattokinase 2000 FU (if fibrinogen high)Serrapeptase 40–120k IU (fibrinolytic)
ZonulinBIOMARKERElevatedGluten-free 6–8 weeks; no alcoholPsyllium/flax fiber; diverse plantsS. boulardii 500mg 2×; L-Glutamine 10gBovine colostrum 500mg; abdominal PBM
HLA-B27GENEPositiveLow-starch diet; sleep 7–9hDaily spinal mobility; manage stressL. acidophilus NCFM + B. lactis Bi-07Infrared sauna 3×/week (HSP induction)
ERAP1GENERisk alleleZinc foods: oysters, pumpkin seedsEliminate alcohol (depletes zinc)Zinc bisglycinate 15–30mg + copper 1–2mgEGCG (green tea extract) 400–800mg
IL23RGENERisk alleleDiverse plant fiber; 30 foods/weekFermented foods; reduce animal fatMelatonin 0.5–3mg; nigella sativa 500mgVitamin D3 + K2 (VDR/IL-23R synergy)
STAT3GENERisk variant16:8 eating window; aerobic exerciseStable blood glucose; reduce IL-6Quercetin 500–1000mg + bromelain; EGCGBerberine 500mg 2–3× (AMPK activation)
KIF21BGENERisk variantSleep: 17–19°C, dark, fixed timingPain management; cortisol reductionAstaxanthin 4–12mg; phosphatidylserineAshwagandha KSM-66 300–600mg