DVT Risk Factors: Genes & BiomarkersGene / BiomarkerBad ScoreFree ActionsNon-free ActionsGENESF5 (Factor V Leiden)MutationWalk, hydrate, compressionAnticoag. (Rx)F2 (Prothrombin)MutationAvoid immobility, exerciseAnticoag. (Rx)MTHFR C677THomozygousB-vitamins, folate-rich dietMethylfolate suppl.SERPINC1 (AT-III)<80% activityStay active, hydrateAntithrombin (Rx)PROC (Protein C)<70% activityExercise regularlyProtein C (Rx)PROS1 (Protein S)<60% free levelNo smoking, walk dailyVit.K antagonistsBIOMARKERSD-dimer>500 ng/mLWalk, hydrateImaging, anticoag. (Rx)Homocysteine>15 µmol/LB6, B12, folate dietB-complex suppl.Fibrinogen>400 mg/dLExercise, clean dietOmega-3 suppl.Factor VIII>150%Aerobic exercise dailyAnticoag. (Rx)Lipoprotein(a)>30 mg/dLLow-fat diet, exerciseNiacin, PCSK9 inhibitorsCRP (C-reactive protein)>3 mg/LAnti-inflam. diet, sleepFish oil, curcuminPlatelet count>450K/µLHydrate, no NSAIDsLow-dose aspirin (Rx)