Knee Contusion — Genes & Biomarkers Recovery Guide
Gene / Biomarker
Bad Score
Free Actions
Non-free Actions
GENES
COL1A1
Poor allele (T/T)
Eccentric loading, collagen diet
PRP injection
MMP3
High expression
RICE protocol, anti-inflam diet
Corticosteroid injection
IL6
Risk allele (C/C)
Cold therapy, rest, compression
Prescription NSAIDs
TNF
Risk allele (A/A)
Elevation, compression, rest
Biologic therapy
BIOMARKERS
CRP
>10 mg/L
Rest, ice pack, omega-3 diet
IV anti-inflammatory
IL-6 protein
>7 pg/mL
Cold pack, anti-inflam food
Tocilizumab (biologic)
COMP
Elevated (>12 U/L)
Low-impact rehab, no loading
Viscosupplementation
Hyaluronic Acid
Low (<1.5 mg/mL)
Hydration, rest, gentle mobility
HA intra-articular injection
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