Longevity Genes & Biomarkers — Scores & Actions
Biomarker / Gene
Suboptimal Score
Free Actions
Non-free Actions
GENES
BIOMARKERS
APOE ε4ε4 allele carrierAvoid sat. fats; aerobic exerciseGenotyping; statins; PCSK9i
FOXO3Minor allele absentIntermittent fasting; exerciseMetformin (off-label)
MTORHyperactivatedCaloric restriction; fastingRapamycin (off-label)
SIRT1Low NAD+ fluxFasting; resveratrol-rich foodsNMN / NR supplements
KLOTHOLow expressionResistance training; sunlightKlotho-boosting peptides
CETPHigh CETP activityMediterranean diet; omega-3sCETP inhibitors
HbA1c>5.6%Low-carb diet; daily walkingCGM; metformin
hs-CRP>1 mg/LAnti-inflam. diet; 7-9h sleepStatins; low-dose aspirin
IGF-1>200 ng/mLProtein cycling; fastingSomatostatin analogs
ApoB / LDLApoB >90 mg/dLPlant-based diet; fiberStatins; PCSK9 inhibitors
Homocysteine>10 µmol/LLeafy greens; B-vitamin foodsB12/folate supplements
Telomere LengthShort telomeresQuality sleep; stress reductionTA-65; telomerase activators