Lyme Disease — Biomarkers & Genes: Bad Scores & Action Plans
Biomarker / Gene
Bad Score / Risk
Free Plan
Plan With Purchases
BIOMARKERS
CD57 NK Cells
Biomarker · immune function
Below 60 cells/µL
(critical: <20 cells/µL)
Sleep 8–9h; anti-inflam. diet;
30 min walk/day; sauna
3×/week at 170°F
Beta-glucans 500mg; Reishi
1,000–3,000mg; Lactoferrin
300mg twice daily
hs-CRP
Biomarker · inflammation
Above 1 mg/L
(significant: >3 mg/L)
Eliminate seed oils; Med. diet;
sleep 7–9h; time-restricted
eating (16:8 window)
Omega-3 2–4g EPA+DHA;
Curcumin+piperine 500mg ×2;
LLLT 630–660nm 3×/week
Salivary Cortisol (4-pt)
Biomarker · HPA axis
Flat AM / elevated PM
curve (dysrhythmia)
Morning light 10–20 min;
delay caffeine 90 min; cold
shower AM; morning exercise
Ashwagandha KSM-66 300–600mg
PM; Phosphatidylserine 400mg;
Rhodiola 200–400mg AM
Thyroid Panel
Biomarker · TSH/T3/T4/rT3/TPO
Low Free T3, high rT3
(>15 ng/dL); TPO Ab high
Address inflammation; 2–3
Brazil nuts/day; avoid low-cal.
dieting; correct iron first
Selenium 200mcg selenometh.;
Zinc 25–30mg + Copper 2mg;
consider low-dose T3 (Rx)
25-OH Vitamin D
Biomarker · immune hormone
Below 60 ng/mL
(optimal: 60–80 ng/mL)
Midday sun 15–30 min on
large skin areas; fatty fish;
egg yolks
D3 5,000 IU + K2-MK7 100mcg;
Magnesium glycinate 300–400mg
(required cofactor for D3)
CBC + Ferritin
Biomarker · immune balance/iron
Lymphopenia / ferritin
<50 ng/mL or elevated
Organ meats, shellfish; pair
iron foods with vit. C; avoid
tea/coffee near iron meals
Iron bisglycinate 25–50mg
every other day (if low); Beta-
glucan + Lactoferrin for lymph.
GENES
HLA-DRB1
Gene · Lyme arthritis risk
*0401 allele present
(autoimmune arthritis risk)
Gluten/dairy elim. 8–12 wks;
contrast hydrotherapy joints;
low-impact exercise only
LDN 1.5–4.5mg (Rx); Boswellia
800mg AKBA ×2; PEA 600mg ×2;
FIR sauna 30 min 3×/week
MTHFR
Gene · methylation bottleneck
C677T / A1298C variants
(60–70% enzyme reduction)
Dark leafy greens, lentils,
liver; avoid synthetic folic
acid; minimize alcohol/stress
5-MTHF 400–1,000mcg + methyl-
cobalamin 1,000mcg; TMG
1,000–3,000mg; monitor HCY
VDR
Gene · vitamin D receptor
Taq / Fok1 polymorphisms
(reduced D receptor sensitivity)
Midday sun 20–30 min on
large skin areas; magnesium-
rich foods; resistant starch
D3+K2 (target 70–90 ng/mL);
Butyrate 600mg ×2 (8-wk
cycles); retest D quarterly
TLR1 / TLR2
Gene · innate immune response
TLR1 1805GG variant
(exaggerated TLR response)
Mediterranean diet; cold
thermogenesis 3–4×/week;
reduce gut permeability
Quercetin 500mg ×2; EGCG
400–800mg; Berberine 500mg
×2 with meals (8-wk cycles)
TNF-alpha -308
Gene · pro-inflam. cytokine
-308A allele present
(high basal TNF-α output)
Fasting (16:8–18:6 window);
grounding 20–30 min/day;
prioritize 8+ hours sleep
Melatonin 3–10mg nightly;
Pterostilbene 500mg; HBOT
1.5–2.0 ATA (physician Rx)
COMT
Gene · catecholamine clearance
Val158Met (met/met)
(40% reduced COMT activity)
Avoid cognitive overload;
moderate aerobic exercise;
minimize caffeine; Mg-rich diet
Mg glycinate 400–600mg PM;
L-theanine 200–400mg; avoid
high-dose methyl-B12 (>1mg)
* Consult a healthcare professional before starting any supplement protocol