Meniscus Tear — Biomarkers & Genes Recovery thresholds and plan access levels Biomarker / Gene Bad Score Free Plan Plan With Purchases BIOMARKERS (7) hs-CRP (C-Reactive Protein) > 3 mg/L Sleep quality, clean diet Omega-3, curcumin, cold immersion IL-6 (Interleukin-6) > 7 pg/mL Weight loss, resistance training Magnesium, Boswellia, red light therapy CTX-II (Collagen Degradation) Elevated Aquatic exercise, reduce knee load UC-II collagen, glucosamine + chondroitin COMP (Cartilage Matrix Protein) > 12 U/L Load management, balance training Hydrolyzed collagen, oral HA + unloader brace 25-OH Vitamin D < 40 ng/mL Sun exposure, fatty fish intake D3 2000–5000 IU/day + K2 (MK-7) MMP-3 (Matrix Metalloproteinase-3) > 28 ng/mL Mediterranean diet, reduce alcohol EGCG, resveratrol, low-dose doxycycline Omega-3 Index (EPA+DHA) < 8% Fatty fish 3–4×/week, reduce seed oils TG-form fish oil 3–4 g EPA+DHA/day GENES (5) COL1A1 (Collagen Type I Alpha 1) T allele Eccentric loading, slow-tempo rehab Hydrolyzed collagen + Vit C + copper MMP3 Gene (Promoter Variant) 5A/5A genotype Mediterranean diet, 7–9 hrs sleep Resveratrol, curcumin, EGCG ACAN (Aggrecan) Short repeats Hydration daily, avoid compression Glucosamine, chondroitin, oral hyaluronic acid VDR (Vitamin D Receptor) Risk variant Sun + resistance training D3 4000–6000 IU + K2 + magnesium glycinate ACTN3 (Alpha-Actinin-3) XX genotype Isometric holds, NMES rehabilitation Creatine, beta-alanine, NMES device Bad Score = threshold above/below which recovery risk is elevated