Genes & Biomarkers for Muscle Growth Gene / Biomarker Suboptimal Score Free Actions Non-free Actions GENES ACTN3R577X / XX genotypeSprint & power trainingSports genomics panel IGF1Low expressionResistance training, proteinrHGH therapy (Rx) MSTNElevated expressionEccentric trainingMyostatin inhibitors PPARGC1AUnfavorable variantEndurance + HIITMitochondrial supplements ACEDD genotypeHIIT intervalsSpecialist consultation BIOMARKERS Testosterone<400 ng/dL (men)Sleep, zinc, vitamin D3TRT (prescription) IGF-1<150 ng/mLProtein intake, sleeprIGF-1 therapy (Rx) Cortisol>20 ug/dL (AM)Stress mgmt, sleepAdaptogens, cortisol blockers Creatine Kinase>500 U/LRest, hydrationNSAIDs, cryotherapy Vitamin D<40 ng/mLSunlight, D3 supplementHigh-dose D3 (Rx) Magnesium<0.85 mmol/LMg-rich foods, supplementIV magnesium Ferritin<30 ng/mLIron-rich foodsIV iron (prescription)