Thyroid Genes & Biomarkers — Summary Table
Gene / Biomarker
Bad Score / Variant
Free Actions
Supplement / Equipment
GENES
TPO
rs2268458 A allele
Selenium diet; manage stress
Selenium 200 mcg/day
DIO2
rs225014 T/T genotype
Optimize zinc & selenium intake
Liothyronine (T3)
TSHR
rs179247 risk allele
Avoid excess iodine
Dose review with MD
BIOMARKERS
TSH
> 4.5 mIU/L
Sleep hygiene; limit stress
Levothyroxine (T4)
Free T4
< 0.8 ng/dL
Iodine-rich foods (seaweed, fish)
T4 dose titration
Free T3
< 2.3 pg/mL
Iron, zinc, selenium diet
T3 or NDT therapy
Anti-TPO Ab
> 35 IU/mL
Gluten-free / AIP protocol
Selenium + LDN